Dissection of Minimal Sequence Requirements for Rhoptry Membrane Targeting in the Malaria Parasite
نویسندگان
چکیده
منابع مشابه
Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite.
Rhoptries are specialized secretory organelles characteristic of single cell organisms belonging to the clade Apicomplexa. These organelles play a key role in the invasion process of host cells by accumulating and subsequently secreting an unknown number of proteins mediating host cell entry. Despite their essential role, little is known about their biogenesis, components and targeting determin...
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Targeting of a Transporter to the Outer Apicoplast Membrane in the Human Malaria Parasite Plasmodium falciparum
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One of the key processes in the pathobiology of the malaria parasite is the invasion and subsequent modification of the human erythrocyte. In this complex process, an unknown number of parasite proteins are involved, some of which are leading vaccine candidates. The majority of the proteins that play pivotal roles in invasion are either stored in the apical secretory organelles or located on th...
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ژورنال
عنوان ژورنال: Traffic
سال: 2012
ISSN: 1398-9219
DOI: 10.1111/j.1600-0854.2012.01394.x